工作经历

教育背景

论文及专利

1.Yang, L.;Lei, C.-H.; Wang, D.-X.; Huang, Z.-T.; Wang, M.-X.* Highly Efficient and Expedient Synthesis of 5-Hydroxy-1H-pyrrol-2-(5H)-ones from FeCl₃-Catalyzed Tandem Intramolecular Enaminic Addition of Tertiary Enamides to Ketones and 1,3-Hydroxy Rearrangement.Org. Lett.2010,12,3918-3921. Times cited: 58.

2.Lei, C.-H.; Wang, D.-X.; Zhao, L.; Zhu, J.; Wang, M.-X.*Synthesis of Substituted Pyridines from Cascade [1+5] Cycloaddition of Isonitriles toN-Formylmethyl-Substituted Enamides, Aerobic Oxidative Aromatization, and Acyl Transfer Reaction.J. Am. Chem. Soc.2013,135, 4708-4711. Times cited: 140.

3.Lei, C.-H.; Wang, D.-X.; Zhao, L.; Zhu, J.; Wang, M.-X.* Synthesis of Multifunctionalized 1,2,3,4-Tetrahydropyridines, 2,3-Dihydropyridin-4(1H)-ones and Pyridines from Tandem Reactions Initiated by [5+1] Cycloaddition ofN-Formylmethyl-Substituted Enamides to Isocyanides: Mechanistic Insight and Synthetic Application.Chem. Eur. J.2013,19, 16981-16987. Times cited: 30.

4.Lei, C.-H.; Zhao, L.; Wang, D.-X.; Zhu, J.; Wang, M.-X.* Functionalized Imidazoliniums from the Three-Component Domino Reaction ofN-Formylmethylcarboxamides with Amines and Isocyanides.Org. Chem. Front.2014,1, 909-913. Times cited: 19.

5.Wu, X.;Lei, C.; Yue, G.; Zhou, J. S.* Palladium-Catalyzed Direct Cyclopropylation of Heterocycles.Angew. Chem. Int. Ed.2015,54, 9601-9605.Times cited: 15.

6.Lei, C.; Jin, X.; Zhou, J. S.* Palladium-Catalyzed Heteroarylation and Concomitantortho-Alkylation of Aryl Iodides.Angew. Chem. Int. Ed.2015,54, 13397-13400. Times cited: 43.

7.Lei, C.; Jin, X.; Zhou, J. S.* Palladium-Catalyzed Alkynylation and ConcomitantorthoAlkylation of Aryl Iodides.ACS Catalysis2016,6, 1635-1639. Times cited: 27.

8.Lei, C.; Cao, J.; Zhou, J. S.* Palladium-Catalyzed Arylation of Ketones and Acetonitrile withortho-Alkylation of Aryl Rings: de novo Synthesis of Tetralines and Benzocycloheptenes.Org. Lett.2016,18, 6120-6123. Times cited: 13.

9.Lei, C.; Yip, Y. J.; Zhou, J. S.* Nickel-Catalyzed Direct Synthesis of Aryl Olefins from Ketones and Organoboron Reagents under Neutral Conditions.J. Am. Chem. Soc.2017,139, 6086-6089. Times cited: 18. One of most read JACS papers of the month.

10. Xu, X.-M.;Lei, C.-H.; Tong, S.; Zhu, J.; Wang, M.-X.* Lewis Acid Catalyst-steered Divergent Synthesis of Functionalized Vicinal Amino Alcohols and Pyrroles from Tertiary Enamides.Org. Chem. Front.2018,5,3138-3142. (co-first author) Times cited: 5.

11. Liu, J.;Lei, C.;* Gong, H.* Nickel-catalyzed reductive coupling of glucosyl halides with aryl/vinyl halides enabling β-selective preparation of C-aryl/vinyl glucosides.Sci. China Chem.2019, 62, 1492-1496.

12. Meng, F.; Zhang, X.; Sarma, T.; Yuan, N.; Yin, Y.; Duan, Z.;Lei, C.;* Qian, Q.;* Ding, L.;* Zhang, Z.* A Poly(pyridine-pyrrole) Foldamer that Binds Isolated Water Molecules.CrystEngComm2019,21,3906-3909.

13. Wang, F.; Sikma, E.; Duan, Z.; Sarma, T.;Lei, C.; Zhang, Z.; Humphrey, S. M.; Sessler, J. L. Shape-persistent Pyrrole-based Covalent Organic Cages: Synthesis, Structure and Selective Gas Adsorption Properties.Chem. Commun.2019,55,6185-6188.

14.Lei, C.; Zhu, D.; Tangcueco, V. I. T.; Zhou, J. S.* Arylation of Aldehydes to Directly Form Ketones via Tandem Nickel Catalysis.Org. Lett.2019, 21, 5817-5822. One of most read Org Lett papers of the month.

15. Ye, D.; Liu, Z.; Chen, H.; Sessler, J. L.;*Lei, C.* Esterification ofN-Benzyl-N-Boc Amides under Ambient Conditions.Org. Lett.2019, 21, 6888-6892.

16. Zhu, Q.; Meng, B.; Gu, C.; Xu, Y.; Chen, J.;Lei, C.;* Wu, X.* Diastereo- and Enantioselective Synthesis of Quaternary alpha-Amino Acid Precursors by Copper-Catalyzed Propargylation.Org. Lett.2019,21, 9985-9989.

17. Wang, F.; Sen, S.; Chen, C.; Bähring, S.;*Lei, C.;* Duan, Z.; Zhang, Z.;* Sessler, J. L.;* Jana, A.* Self-Assembled Cagelike Receptor That Binds Biologically Relevant Dicarboxylic Acids via Proton-Coupled Anion Recognition.J. Am. Chem. Soc.2020,142, 1987-1994. DOI: 10.1021/jacs.9b11566.

18. Xia, S.; Hu, K.;Lei, C.;* Jin, J.* Intramolecular Aromatic C–H Acyloxylation Enabled by Iron Photocatalysis.Org. Lett.2020,22, 1385-1389. DOI: 10.1021/acs.orglett.0c00002.

19. Kim, T.; Duan, Z.; Talukdar, S.;Lei, C.;* Kim, D.;* Sessler, J. L.;* Sarma, T.* Excitonically Coupled Cyclic BF₂Arrays of Calix[8]- and Calix[16]phyrin as Near-IR-Chromophores.Angew. Chem. Int. Ed.2020, accepted. DOI: 10.1002/anie.202004867.

Patent:

1.王梅祥，雷川虎，王德先。专利：多取代二氢吡啶-4-酮类化合物及其制备方法与应用。申请号：CN 201310134018.6，授权公告号：CN 104109113B.

2.雷川虎，叶丹锋，刘志园，陈闯。专利：以N-Boc酰胺为原料合成酯类化合物的制备方法。申请号：CN 2018113817347.0.

学术报告

1. The³rd International Conference on Molecular & Functional Catalysis (ICFMC-3),口头报告（英文），新加坡，2017年2月28日，报告题目：Palladium-Catalyzed C-H Functionalization of Aryl Iodides and Nickel-Catalyzed Arylation of Ketones and Aldehydes

2. The¹⁴th International Symposium for Chinese Organic Chemists (ISCOC)，邀请报告（英文），新加坡，2016年12月10日，报告题目：Palladium and Norbornene-Cocatalyzed C-H Functionalization of Aryl Iodides

3. 第六届“CCME-IOC & ICCAS-LMRF”Alfa Aesar研究生学术研讨会，口头报告（中文），北京，2013年3月2日，报告题目：基于官能化烯酰胺与异腈串联反应的研究

获奖情况

2020 上海市2020年度“启明星”计划

2018 上海市高校特聘教授（东方学者）

2012 中科院化学所青年科学优秀奖，中科院化学所“凯莱英”研究生系列报告优秀报告奖

2008 北京市优秀毕业生，北京师范大学优秀毕业生，北京师范大学优秀毕业论文

2007 北京师范大学专业一等奖学金、优秀学生干部

2006 北京师范大学专业二等奖学金、优秀学生干部

2005 北京师范大学专业二等奖学金

2004 四川省优秀学生干部

基金资助

1. 上海市2020年度“科技创新行动计划”启明星计划2020.06-2023.12

2. 上海市高校特聘教授（东方学者）2019.07-2022.08

3. 国家自然科学基金青年基金201901155，2020.01-2022.12

4. 上海市教委青年教师科研专项基金2020.01-2022.12

联系方式 021-66135155; chl@shu.edu.cn